Engineering bacteria to biosynthesize intricate protein complexes

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Protein cages found in nature within microbes help weather its contents from the harsh intracellular environment — an observation with many bioengineering applications. Researchers recently developed an innovative bioengineering approach using genetically modified bacteria; these bacteria can incorporate protein cages around protein crystals. This in-cell biosynthesis method efficiently produces highly customized protein complexes, which could find applications as advanced solid catalysts and functionalized nanomaterials.
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